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Silencing of Parkinson's disease-associated genes with artificial mirtron mimics of miR-1224

Mirtrons are a recently described category of microRNA (miRNA) relying on splicing rather than processing by the microprocessor complex to generate pre-miRNA precursors of the RNA interference (RNAi) pathway. Their discovery and subsequent verification provides important information about a distinct...

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Detalles Bibliográficos
Autores principales: Sibley, Christopher R., Seow, Yiqi, Curtis, Helen, Weinberg, Marc S., Wood, Matthew J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479180/
https://www.ncbi.nlm.nih.gov/pubmed/22848108
http://dx.doi.org/10.1093/nar/gks712