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Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structures
Bloom (BLM) syndrome is an autosomal recessive disorder characterized by an increased risk for many types of cancers. Previous studies have shown that BLM protein forms a hexameric ring structure, but its oligomeric form in DNA unwinding is still not well clarified. In this work, we have used dynami...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479192/ https://www.ncbi.nlm.nih.gov/pubmed/22885301 http://dx.doi.org/10.1093/nar/gks728 |