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Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability

The majority of Cockayne syndrome (CS) patients carry a mutation in Cockayne Syndrome group B (CSB), a large nuclear protein implicated in DNA repair, transcription and chromatin remodeling. However, whether CSB may play a role in telomere metabolism has not yet been characterized. Here, we report t...

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Detalles Bibliográficos
Autores principales: Batenburg, Nicole L., Mitchell, Taylor R. H., Leach, Derrik M., Rainbow, Andrew J., Zhu, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479199/
https://www.ncbi.nlm.nih.gov/pubmed/22904069
http://dx.doi.org/10.1093/nar/gks745