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Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases

Adenosine deaminases acting on RNA (ADAR1 and ADAR2) are human RNA-editing adenosine deaminases responsible for the conversion of adenosine to inosine at specific locations in cellular RNAs. Since inosine is recognized during translation as guanosine, this often results in the expression of protein...

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Detalles Bibliográficos
Autores principales: Mizrahi, Rena A., Phelps, Kelly J., Ching, Andrea Y., Beal, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479202/
https://www.ncbi.nlm.nih.gov/pubmed/22885375
http://dx.doi.org/10.1093/nar/gks752