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PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition

The extracellular matrix protein Laminin B1 (LamB1) regulates tumor cell migration and invasion. Carcinoma cells acquire invasive properties by epithelial to mesenchymal transition (EMT), which is a fundamental step in dissemination of metastatic cells from the primary tumor. Recently, we showed tha...

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Detalles Bibliográficos
Autores principales: Petz, Michaela, Them, Nicole C. C., Huber, Heidemarie, Mikulits, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479205/
https://www.ncbi.nlm.nih.gov/pubmed/22904067
http://dx.doi.org/10.1093/nar/gks760