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Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens

PURPOSE: Monomeric IgE molecules, when bound to the high-affinity receptor, exhibit a vast heterogeneity in their ability to induce survival promotion and cytokine production in mast cells. At one end of this spectrum, highly cytokinergic (HC) IgEs can induce potent survival promotion, degranulation...

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Detalles Bibliográficos
Autores principales: Kashiwakura, Jun-ichi, Okayama, Yoshimichi, Furue, Masutaka, Kabashima, Kenji, Shimada, Shinji, Ra, Chisei, Siraganian, Reuben P., Kawakami, Yuko, Kawakami, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479226/
https://www.ncbi.nlm.nih.gov/pubmed/23115729
http://dx.doi.org/10.4168/aair.2012.4.6.332