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Epithelial Wnt ligand secretion is required for adult hair follicle growth and regeneration

β-catenin, a key transducer molecule of Wnt signaling, is required for adult hair follicle growth and regeneration. However, the cellular source of Wnt ligands required for Wnt/β-catenin activation during anagen induction is unknown. In this study, we genetically deleted Wntless, a gene required for...

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Detalles Bibliográficos
Autores principales: Myung, Peggy, Takeo, Makoto, Ito, Mayumi, Atit, Radhika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479363/
https://www.ncbi.nlm.nih.gov/pubmed/22810306
http://dx.doi.org/10.1038/jid.2012.230