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Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library

BACKGROUND: While there is strong evidence for phosphatidylinositol 3-kinase (PI3K) involvement in cancer development, there is limited information about the role of PI3K regulatory subunits. PIK3R3, the gene that encodes the PI3K regulatory subunit p55γ, is over-expressed in glioblastoma and ovaria...

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Detalles Bibliográficos
Autores principales: Zhou, Jin, Chen, Geng Bo, Tang, Yew Chung, Sinha, Rohit Anthony, Wu, Yonghui, Yap, Chui Sun, Wang, Guihua, Hu, Junbo, Xia, Xianmin, Tan, Patrick, Goh, Liang Kee, Yen, Paul Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479415/
https://www.ncbi.nlm.nih.gov/pubmed/22876838
http://dx.doi.org/10.1186/1755-8794-5-34