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Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner

BACKGROUND: There is strong but mostly circumstantial evidence that genetic factors modulate the severity of influenza infection in humans. Using genetically diverse but fully inbred strains of mice it has been shown that host sequence variants have a strong influence on the severity of influenza A...

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Detalles Bibliográficos
Autores principales: Nedelko, Tatiana, Kollmus, Heike, Klawonn, Frank, Spijker, Sabine, Lu, Lu, Heßman, Manuela, Alberts, Rudi, Williams, Robert W, Schughart, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479429/
https://www.ncbi.nlm.nih.gov/pubmed/22905720
http://dx.doi.org/10.1186/1471-2164-13-411