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Loss of E-cadherin and Acquisition of Vimentin in Epithelial-Mesenchymal Transition are Noble Indicators of Uterine Cervix Cancer Progression
BACKGROUND: Epithelial-mesenchymal transition (EMT) has been known to play a key role in the stromal invasion of carcinoma in situ (CIS) lesion. Loss of E-cadherin and acquisition of vimentin are two critical steps in EMT, that are induced by Snail-1 upregulation associated with overexpression of ep...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Society of Pathologists and The Korean Society for Cytopathology
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479821/ https://www.ncbi.nlm.nih.gov/pubmed/23110026 http://dx.doi.org/10.4132/KoreanJPathol.2012.46.4.341 |