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Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices

The culture liver slices are mainly used to investigate drug metabolism and xenobiotic-mediated liver injuries while apoptosis and proliferation remain unexplored in this culture model. Here, we show a transient increase in LDH release and caspase activities indicating an ischemic injury during the...

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Detalles Bibliográficos
Autores principales: Finot, Francis, Masson, Régis, Desmots, Fabienne, Ribault, Catherine, Bichet, Nicole, Vericat, Joan A., Lafouge, Patricia, Guguen-Guillouzo, Christiane, Loyer, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480011/
https://www.ncbi.nlm.nih.gov/pubmed/23119170
http://dx.doi.org/10.1155/2012/785786