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Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis

Chronic kidney disease (CKD) remains one of the leading causes of death in the developed world and acute kidney injury (AKI) is now recognized as a major risk factor in its development. Understanding the factors leading to CKD after acute injury are limited by current animal models of AKI which conc...

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Detalles Bibliográficos
Autores principales: Grgic, Ivica, Campanholle, Gabriela, Bijol, Vanesa, Wang, Chang, Sabbisetti, Venkata S., Ichimura, Takaharu, Humphreys, Benjamin D., Bonventre, Joseph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480325/
https://www.ncbi.nlm.nih.gov/pubmed/22437410
http://dx.doi.org/10.1038/ki.2012.20