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Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ(12,14)-Prostaglandin J(2) through Oxidative Stress in Human Neutrophils
Liver X receptors (LXRs) are ligand-activated transcription factors of the nuclear receptor superfamily. They play important roles in controlling cholesterol homeostasis and as regulators of inflammatory gene expression and innate immunity, by blunting the induction of classical pro-inflammatory gen...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480349/ https://www.ncbi.nlm.nih.gov/pubmed/23115616 http://dx.doi.org/10.1371/journal.pone.0042195 |