Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5

Severe influenza infections are complicated by acute lung injury, a syndrome of pulmonary microvascular leak. The pathogenesis of this complication is unclear. We hypothesized that human influenza could directly infect the lung microvascular endothelium, leading to loss of endothelial barrier functi...

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Detalles Bibliográficos
Autores principales: Armstrong, Susan M., Wang, Changsen, Tigdi, Jayesh, Si, Xiaoe, Dumpit, Carlo, Charles, Steffany, Gamage, Asela, Moraes, Theo J., Lee, Warren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480371/
https://www.ncbi.nlm.nih.gov/pubmed/23115643
http://dx.doi.org/10.1371/journal.pone.0047323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480371/
https://www.ncbi.nlm.nih.gov/pubmed/23115643
http://dx.doi.org/10.1371/journal.pone.0047323

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