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Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7

Elevated expression and activity of the epidermal growth factor receptor (EGFR)/protein kinase B (Akt) signaling pathway is associated with development, progression and treatment resistance of head and neck cancer (HNC). Several studies have demonstrated that microRNA-7 (miR-7) regulates EGFR expres...

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Detalles Bibliográficos
Autores principales: Kalinowski, Felicity C., Giles, Keith M., Candy, Patrick A., Ali, Alishum, Ganda, Clarissa, Epis, Michael R., Webster, Rebecca J., Leedman, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480380/
https://www.ncbi.nlm.nih.gov/pubmed/23115635
http://dx.doi.org/10.1371/journal.pone.0047067