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Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7
Elevated expression and activity of the epidermal growth factor receptor (EGFR)/protein kinase B (Akt) signaling pathway is associated with development, progression and treatment resistance of head and neck cancer (HNC). Several studies have demonstrated that microRNA-7 (miR-7) regulates EGFR expres...
Autores principales: | Kalinowski, Felicity C., Giles, Keith M., Candy, Patrick A., Ali, Alishum, Ganda, Clarissa, Epis, Michael R., Webster, Rebecca J., Leedman, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480380/ https://www.ncbi.nlm.nih.gov/pubmed/23115635 http://dx.doi.org/10.1371/journal.pone.0047067 |
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