Deletion of the gabra2 Gene Results in Hypersensitivity to the Acute Effects of Ethanol but Does Not Alter Ethanol Self Administration

Human genetic studies have suggested that polymorphisms of the GABRA2 gene encoding the GABA(A) α2-subunit are associated with ethanol dependence. Variations in this gene also convey sensitivity to the subjective effects of ethanol, indicating a role in mediating ethanol-related behaviours. We there...

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Detalles Bibliográficos
Autores principales: Dixon, Claire I., Walker, Sophie E., King, Sarah L., Stephens, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480382/
https://www.ncbi.nlm.nih.gov/pubmed/23115637
http://dx.doi.org/10.1371/journal.pone.0047135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480382/
https://www.ncbi.nlm.nih.gov/pubmed/23115637
http://dx.doi.org/10.1371/journal.pone.0047135

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