SIV Genome-Wide Pyrosequencing Provides a Comprehensive and Unbiased View of Variation within and outside CD8 T Lymphocyte Epitopes

Deep sequencing technology is revolutionizing our understanding of HIV/SIV evolution. It is known that acute SIV sequence variation within CD8 T lymphocyte (CD8-TL) epitopes is similar among MHC-identical animals, but we do not know whether this persists into the chronic phase. We now determine whet...

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Detalles Bibliográficos
Autores principales: Hughes, Austin L., Becker, Ericka A., Lauck, Michael, Karl, Julie A., Braasch, Andrew T., O’Connor, David H., O’Connor, Shelby L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480401/
https://www.ncbi.nlm.nih.gov/pubmed/23112852
http://dx.doi.org/10.1371/journal.pone.0047818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480401/
https://www.ncbi.nlm.nih.gov/pubmed/23112852
http://dx.doi.org/10.1371/journal.pone.0047818

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