The Apolipoprotein E (APOE) Gene Appears Functionally Monomorphic in Chimpanzees (Pan troglodytes)

BACKGROUND: The human apolipoprotein E (APOE) gene is polymorphic, with three primary alleles (E2, E3, E4) that differ at two key non-synonymous sites. These alleles are functionally different in how they bind to lipoproteins, and this genetic variation is associated with phenotypic variation for se...

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Detalles Bibliográficos
Autores principales: McIntosh, Annick M., Bennett, Calvin, Dickson, Dara, Anestis, Stephanie F., Watts, David P., Webster, Timothy H., Fontenot, M. Babette, Bradley, Brenda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480407/
https://www.ncbi.nlm.nih.gov/pubmed/23112842
http://dx.doi.org/10.1371/journal.pone.0047760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480407/
https://www.ncbi.nlm.nih.gov/pubmed/23112842
http://dx.doi.org/10.1371/journal.pone.0047760

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