Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders

Epigenetic changes are involved in a wide range of common human diseases. Although DNA methylation defects are known to be associated with male infertility in mice, their impact on human deficiency of sperm production has yet to be determined. We have assessed the global genomic DNA methylation prof...

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Detalles Bibliográficos
Autores principales: Heyn, Holger, Ferreira, Humberto J., Bassas, Lluís, Bonache, Sandra, Sayols, Sergi, Sandoval, Juan, Esteller, Manel, Larriba, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480440/
https://www.ncbi.nlm.nih.gov/pubmed/23112866
http://dx.doi.org/10.1371/journal.pone.0047892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480440/
https://www.ncbi.nlm.nih.gov/pubmed/23112866
http://dx.doi.org/10.1371/journal.pone.0047892

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