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Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders
Epigenetic changes are involved in a wide range of common human diseases. Although DNA methylation defects are known to be associated with male infertility in mice, their impact on human deficiency of sperm production has yet to be determined. We have assessed the global genomic DNA methylation prof...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480440/ https://www.ncbi.nlm.nih.gov/pubmed/23112866 http://dx.doi.org/10.1371/journal.pone.0047892 |