The AprV5 Subtilase Is Required for the Optimal Processing of All Three Extracellular Serine Proteases from Dichelobacter nodosus

Dichelobacter nodosus is the principal causative agent of ovine footrot and its extracellular proteases are major virulence factors. Virulent isolates of D. nodosus secrete three subtilisin-like serine proteases: AprV2, AprV5 and BprV. These enzymes are each synthesized as precursor molecules that i...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiaoyan, Kennan, Ruth M., Steer, David L., Smith, A. Ian, Whisstock, James C., Rood, Julian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480457/
https://www.ncbi.nlm.nih.gov/pubmed/23112874
http://dx.doi.org/10.1371/journal.pone.0047932