ReFlexIn: A Flexible Receptor Protein-Ligand Docking Scheme Evaluated on HIV-1 Protease

For many targets of pharmaceutical importance conformational changes of the receptor protein are relevant during the ligand binding process. A new docking approach, ReFlexIn (Receptor Flexibility by Interpolation), that combines receptor flexibility with the computationally efficient potential grid...

Descripción completa

Detalles Bibliográficos
Autores principales: Leis, Simon, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480487/
https://www.ncbi.nlm.nih.gov/pubmed/23110159
http://dx.doi.org/10.1371/journal.pone.0048008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480487/
https://www.ncbi.nlm.nih.gov/pubmed/23110159
http://dx.doi.org/10.1371/journal.pone.0048008

Ejemplares similares