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Zinc Transporter ZIP14 Functions in Hepatic Zinc, Iron and Glucose Homeostasis during the Innate Immune Response (Endotoxemia)

ZIP14 (slc39A14) is a zinc transporter induced in response to pro-inflammatory stimuli. ZIP14 induction accompanies the reduction in serum zinc (hypozincemia) of acute inflammation. ZIP14 can transport Zn(2+) and non-transferrin-bound Fe(2+) in vitro. Using a Zip14(−/−) mouse model we demonstrated t...

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Detalles Bibliográficos
Autores principales: Beker Aydemir, Tolunay, Chang, Shou-Mei, Guthrie, Gregory J., Maki, Alyssa B., Ryu, Moon-Suhn, Karabiyik, Afife, Cousins, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480510/
https://www.ncbi.nlm.nih.gov/pubmed/23110240
http://dx.doi.org/10.1371/journal.pone.0048679