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Biochemical characterization of recombinant Candida albicans mannosyltransferases Mnt1, Mnt2 and Mnt5 reveals new functions in O- and N-mannan biosynthesis

The cell surface of Candida albicans is enriched with highly glycosylated mannoproteins that are involved in the interaction with host tissues. N- and O-glycosylation are post-translational modifications that initiate in the endoplasmic reticulum, and finalize in the Golgi. The KRE2/MNT1 family enco...

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Detalles Bibliográficos
Autores principales: Díaz-Jiménez, Diana F., Mora-Montes, Héctor M., Hernández-Cervantes, Arturo, Luna-Arias, Juan P., Gow, Neil A.R., Flores-Carreón, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480643/
https://www.ncbi.nlm.nih.gov/pubmed/22326920
http://dx.doi.org/10.1016/j.bbrc.2012.01.131