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From biomarkers to a clue of biology: a computation-aided perspective of immune gene expression profiles in human type 1 diabetes

Dysregulated expression of key immune genes may cause breakdown of immunological tolerance and development of autoimmune disorders such as type 1 diabetes (T1D). General immune insufficiencies have also been implicated as a trigger of autoimmunity, due to their potential impact on immune homeostasis...

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Detalles Bibliográficos
Autores principales: Han, Dongmei, Cai, Xiaodong, Wen, Ji, Kenyon, Norma S., Chen, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480653/
https://www.ncbi.nlm.nih.gov/pubmed/23112798
http://dx.doi.org/10.3389/fimmu.2012.00320