An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis

The biosynthesis of many vitamins and coenzymes has often proved difficult to elucidate due to a combination of low abundance and kinetic lability of the pathway intermediates. Through a serial reconstruction of the cobalamin (vitamin B(12)) pathway in E. coli, and by His-tagging the terminal enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Deery, Evelyne, Schroeder, Susanne, Lawrence, Andrew D., Taylor, Samantha L., Seyedarabi, Arefeh, Waterman, Jitka, Wilson, Keith S., Brown, David, Geeves, Michael A., Howard, Mark J., Pickersgill, Richard W., Warren, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480714/
https://www.ncbi.nlm.nih.gov/pubmed/23042036
http://dx.doi.org/10.1038/nchembio.1086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480714/
https://www.ncbi.nlm.nih.gov/pubmed/23042036
http://dx.doi.org/10.1038/nchembio.1086

Ejemplares similares