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Antidepressant-like activity of (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone (4a), a novel 5-HT(3) receptor antagonist: An investigation in behaviour-based rodent models of depression

AIM: The present study was designed to investigate the antidepressant potential of (4-phenylpiperazin-1-yl) (quinoxalin-3-yl) methanone (4a), a novel 5-HT(3) receptor antagonist, with an optimal log P (2.84) and pA(2) value (7.3) greater than ondansetron (6.9) using rodent behavioural models of depr...

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Detalles Bibliográficos
Autores principales:	Mahesh, Radhakrishnan, Kumar, Baldev, Jindal, Ankur, Bhatt, Shvetank, Devadoss, Thangaraj, Pandey, Dilip Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480784/ https://www.ncbi.nlm.nih.gov/pubmed/23112413 http://dx.doi.org/10.4103/0253-7613.100371

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