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Nimesulide inhibits the proliferation of HepG2 by up-regulation of Smad4

OBJECTIVES: Hepatocellular carcinoma (HCC) is receiving increased attention. This study was designed to investigate the effect of selective Cyclooxygenase-2 (COX-2) inhibitor, nimesulide, on the expression of Smad4 in human hepatocellular carcinoma HepG2. MATERIALS AND METHODS: HepG2 cells were incu...

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Detalles Bibliográficos
Autores principales: Yang, Shaoqi, Guo, Ruifang, Huang, Liya, Yang, Li, Jiang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480792/
https://www.ncbi.nlm.nih.gov/pubmed/23112421
http://dx.doi.org/10.4103/0253-7613.100384