The Triform algorithm: improved sensitivity and specificity in ChIP-Seq peak finding

BACKGROUND: Chromatin immunoprecipitation combined with high-throughput sequencing (ChIP-Seq) is the most frequently used method to identify the binding sites of transcription factors. Active binding sites can be seen as peaks in enrichment profiles when the sequencing reads are mapped to a referenc...

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Detalles Bibliográficos
Autores principales: Kornacker, Karl, Rye, Morten Beck, Håndstad, Tony, Drabløs, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480842/
https://www.ncbi.nlm.nih.gov/pubmed/22827163
http://dx.doi.org/10.1186/1471-2105-13-176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480842/
https://www.ncbi.nlm.nih.gov/pubmed/22827163
http://dx.doi.org/10.1186/1471-2105-13-176

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