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The Triform algorithm: improved sensitivity and specificity in ChIP-Seq peak finding
BACKGROUND: Chromatin immunoprecipitation combined with high-throughput sequencing (ChIP-Seq) is the most frequently used method to identify the binding sites of transcription factors. Active binding sites can be seen as peaks in enrichment profiles when the sequencing reads are mapped to a referenc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480842/ https://www.ncbi.nlm.nih.gov/pubmed/22827163 http://dx.doi.org/10.1186/1471-2105-13-176 |