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Effect of inhibition of the Ubiquitin-Proteasome System and Hsp90 on growth and survival of Rhabdomyosarcoma cells in vitro

BACKGROUND: The ubiquitin-proteasome system (UPS) and the heat shock response (HSR) are two critical regulators of cell homeostasis, as their inhibition affects growth and survival of normal cells, as well as stress response and invasiveness of cancer cells. We evaluated the effects of the proteasom...

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Detalles Bibliográficos
Autores principales: Peron, Marica, Bonvini, Paolo, Rosolen, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480867/
https://www.ncbi.nlm.nih.gov/pubmed/22691173
http://dx.doi.org/10.1186/1471-2407-12-233