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Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria
BACKGROUND: Plasmodium falciparum histidine-rich protein PFHRP2 measurement is used widely for diagnosis, and more recently for severity assessment in falciparum malaria. The Pfhrp2 gene is highly polymorphic, with deletion of the entire gene reported in both laboratory and field isolates. These iss...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480887/ https://www.ncbi.nlm.nih.gov/pubmed/22898068 http://dx.doi.org/10.1186/1475-2875-11-276 |