Regulatory B Cells from Hilar Lymph Nodes of Tolerant Mice in a Murine Model of Allergic Airway Disease are CD5(+), Express TGF-β and Co-localize with CD4(+)Foxp3(+) T Cells

In a biphasic, ovalbumin (OVA)-induced murine asthma model where allergic airway disease is followed by resolution and the development of local inhalational tolerance (LIT), TGFβ-expressing CD5(+) B cells were selectively expanded locally in hilar lymph nodes (HLN) of LIT mice. LIT HLN CD5(+) B cell...

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Detalles Bibliográficos
Autores principales: Natarajan, Prabitha, Singh, Anurag, McNamara, Jeffrey T., Secor, Eric R., Guernsey, Linda A., Thrall, Roger S., Schramm, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480990/
https://www.ncbi.nlm.nih.gov/pubmed/22718263
http://dx.doi.org/10.1038/mi.2012.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480990/
https://www.ncbi.nlm.nih.gov/pubmed/22718263
http://dx.doi.org/10.1038/mi.2012.42

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