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Regulatory B Cells from Hilar Lymph Nodes of Tolerant Mice in a Murine Model of Allergic Airway Disease are CD5(+), Express TGF-β and Co-localize with CD4(+)Foxp3(+) T Cells
In a biphasic, ovalbumin (OVA)-induced murine asthma model where allergic airway disease is followed by resolution and the development of local inhalational tolerance (LIT), TGFβ-expressing CD5(+) B cells were selectively expanded locally in hilar lymph nodes (HLN) of LIT mice. LIT HLN CD5(+) B cell...
Autores principales: | Natarajan, Prabitha, Singh, Anurag, McNamara, Jeffrey T., Secor, Eric R., Guernsey, Linda A., Thrall, Roger S., Schramm, Craig M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480990/ https://www.ncbi.nlm.nih.gov/pubmed/22718263 http://dx.doi.org/10.1038/mi.2012.42 |
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