Visualization of the spatial positioning of the SNRPN, UBE3A, and GABRB3 genes in the normal human nucleus by three-color 3D fluorescence in situ hybridization

The three-dimensional (3D) structure of the genome is organized non-randomly and plays a role in genomic function via epigenetic mechanisms in the eukaryotic nucleus. Here, we analyzed the spatial positioning of three target regions; the SNRPN, UBE3A, and GABRB3 genes on human chromosome 15q11.2–q12...

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Detalles Bibliográficos
Autores principales: Kawamura, Rie, Tanabe, Hideyuki, Wada, Takahito, Saitoh, Shinji, Fukushima, Yoshimitsu, Wakui, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481056/
https://www.ncbi.nlm.nih.gov/pubmed/22801776
http://dx.doi.org/10.1007/s10577-012-9300-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481056/
https://www.ncbi.nlm.nih.gov/pubmed/22801776
http://dx.doi.org/10.1007/s10577-012-9300-5

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