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An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning

Mutations in the human FOXP2 gene cause impaired speech development and linguistic deficits, which have been best characterised in a large pedigree called the KE family. The encoded protein is highly conserved in many vertebrates and is expressed in homologous brain regions required for sensorimotor...

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Detalles Bibliográficos
Autores principales: French, C A, Jin, X, Campbell, T G, Gerfen, E, Groszer, M, Fisher, S E, Costa, R M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481071/
https://www.ncbi.nlm.nih.gov/pubmed/21876543
http://dx.doi.org/10.1038/mp.2011.105