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An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning
Mutations in the human FOXP2 gene cause impaired speech development and linguistic deficits, which have been best characterised in a large pedigree called the KE family. The encoded protein is highly conserved in many vertebrates and is expressed in homologous brain regions required for sensorimotor...
Autores principales: | French, C A, Jin, X, Campbell, T G, Gerfen, E, Groszer, M, Fisher, S E, Costa, R M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481071/ https://www.ncbi.nlm.nih.gov/pubmed/21876543 http://dx.doi.org/10.1038/mp.2011.105 |
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