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Bcl-2 family member Bcl-G is not a proapoptotic protein

The three major subgroups of the Bcl-2 family, including the prosurvival Bcl-2-like proteins, the proapoptotic Bcl-2 homology (BH)3-only proteins and Bax/Bak proteins, regulate the mitochondrial apoptotic pathway. In addition, some outliers within the Bcl-2 family do not fit into these subgroups. On...

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Detalles Bibliográficos
Autores principales: Giam, M, Okamoto, T, Mintern, J D, Strasser, A, Bouillet, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481120/
https://www.ncbi.nlm.nih.gov/pubmed/23059823
http://dx.doi.org/10.1038/cddis.2012.130