A transcriptionally active pRb–E2F1–P/CAF signaling pathway is central to TGFβ-mediated apoptosis

Transforming growth factor-β (TGFβ) modulates the expression of multiple apoptotic target genes; however, a common and central signaling pathway, acting downstream of TGFβ and leading to cell death, has yet to be uncovered. Here, we show that TGFβ-induced apoptosis in cancer cells requires the trans...

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Detalles Bibliográficos
Autores principales: Korah, J, Falah, N, Lacerte, A, Lebrun, J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481134/
https://www.ncbi.nlm.nih.gov/pubmed/23059826
http://dx.doi.org/10.1038/cddis.2012.146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481134/
https://www.ncbi.nlm.nih.gov/pubmed/23059826
http://dx.doi.org/10.1038/cddis.2012.146

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