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Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women

BACKGROUND: Although global hypomethylation of leukocyte DNA has been associated with an increased risk of several sites of cancer, including breast cancer, determinants of global methylation level among healthy individuals remain largely unexplored. Here, we examined whether postmenopausal endogeno...

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Detalles Bibliográficos
Autores principales: Iwasaki, Motoki, Ono, Hiroe, Kuchiba, Aya, Kasuga, Yoshio, Yokoyama, Shiro, Onuma, Hiroshi, Nishimura, Hideki, Kusama, Ritsu, Yoshida, Teruhiko, Tsugane, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481397/
https://www.ncbi.nlm.nih.gov/pubmed/22839213
http://dx.doi.org/10.1186/1471-2407-12-323