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Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling

BACKGROUND: Microglia are resident brain macrophages that can phagocytose dead, dying or viable neurons, which may be beneficial or detrimental in inflammatory, ischaemic and neurodegenerative brain pathologies. Cell death caused by phagocytosis of an otherwise viable cell is called ‘primary phagocy...

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Detalles Bibliográficos
Autores principales: Fricker, Michael, Oliva-Martín, María José, Brown, Guy C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481398/
https://www.ncbi.nlm.nih.gov/pubmed/22889139
http://dx.doi.org/10.1186/1742-2094-9-196