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Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites
BACKGROUND: The identifying of binding sites for transcription factors is a key component of gene regulatory network analysis. This is often done using position-weight matrices (PWMs). Because of the importance of in silico mapping of tentative binding sites, we previously developed an approach for...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481455/ https://www.ncbi.nlm.nih.gov/pubmed/22913572 http://dx.doi.org/10.1186/1471-2164-13-416 |