Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

BACKGROUND: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision. The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secondary genetic and/or epigenetic risk factors are suggested t...

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Detalles Bibliográficos
Autores principales: Aleyasin, A, Ghazanfari, M, Houshmand, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481624/
https://www.ncbi.nlm.nih.gov/pubmed/23113023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481624/
https://www.ncbi.nlm.nih.gov/pubmed/23113023

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