Intraocular pressure variation in patients on long-term corticosteroids
BACKGROUND: Long-term use of topical and systemic steroids produces secondary open-angle glaucoma similar to chronic simple glaucoma. The increased intraocular pressure [IOP] caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible. MATERIALS AND METHODS: In th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications Pvt Ltd
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481806/ https://www.ncbi.nlm.nih.gov/pubmed/23130227 http://dx.doi.org/10.4103/2229-5178.85993 |
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author | Mandapati, John Shekhar Raju Metta, Arun Kumar |
author_facet | Mandapati, John Shekhar Raju Metta, Arun Kumar |
author_sort | Mandapati, John Shekhar Raju |
collection | PubMed |
description | BACKGROUND: Long-term use of topical and systemic steroids produces secondary open-angle glaucoma similar to chronic simple glaucoma. The increased intraocular pressure [IOP] caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible. MATERIALS AND METHODS: In this study, we analyzed 200 patients with steroid-induced glaucoma, who were on systemic and topical corticosteroids for various dermatological conditions. The variation in IOP caused by different steroid preparations was studied. RESULTS: Two hundred patients who were on systemic steroids for more than 8 weeks developed raised IOP. Three of these patients also developed bilateral posterior subcapsular cataract. CONCLUSION: We conclude that systemic steroids can induce rise of IOP and cataract formation. If it is not detected and treated in time, rise in IOP can lead to irreversible damage to the eyes. |
format | Online Article Text |
id | pubmed-3481806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34818062012-11-05 Intraocular pressure variation in patients on long-term corticosteroids Mandapati, John Shekhar Raju Metta, Arun Kumar Indian Dermatol Online J Original Article BACKGROUND: Long-term use of topical and systemic steroids produces secondary open-angle glaucoma similar to chronic simple glaucoma. The increased intraocular pressure [IOP] caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible. MATERIALS AND METHODS: In this study, we analyzed 200 patients with steroid-induced glaucoma, who were on systemic and topical corticosteroids for various dermatological conditions. The variation in IOP caused by different steroid preparations was studied. RESULTS: Two hundred patients who were on systemic steroids for more than 8 weeks developed raised IOP. Three of these patients also developed bilateral posterior subcapsular cataract. CONCLUSION: We conclude that systemic steroids can induce rise of IOP and cataract formation. If it is not detected and treated in time, rise in IOP can lead to irreversible damage to the eyes. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3481806/ /pubmed/23130227 http://dx.doi.org/10.4103/2229-5178.85993 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mandapati, John Shekhar Raju Metta, Arun Kumar Intraocular pressure variation in patients on long-term corticosteroids |
title | Intraocular pressure variation in patients on long-term corticosteroids |
title_full | Intraocular pressure variation in patients on long-term corticosteroids |
title_fullStr | Intraocular pressure variation in patients on long-term corticosteroids |
title_full_unstemmed | Intraocular pressure variation in patients on long-term corticosteroids |
title_short | Intraocular pressure variation in patients on long-term corticosteroids |
title_sort | intraocular pressure variation in patients on long-term corticosteroids |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481806/ https://www.ncbi.nlm.nih.gov/pubmed/23130227 http://dx.doi.org/10.4103/2229-5178.85993 |
work_keys_str_mv | AT mandapatijohnshekharraju intraocularpressurevariationinpatientsonlongtermcorticosteroids AT mettaarunkumar intraocularpressurevariationinpatientsonlongtermcorticosteroids |