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Review of meta-analyses evaluating surrogate endpoints for overall survival in oncology

Overall survival (OS) is the gold standard in measuring the treatment effect of new drug therapies for cancer. However, practical factors may preclude the collection of unconfounded OS data, and surrogate endpoints are often used instead. Meta-analyses have been widely used for the validation of sur...

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Detalles Bibliográficos
Autores principales: Sherrill, Beth, Kaye, James A, Sandin, Rickard, Cappelleri, Joseph C, Chen, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481854/
https://www.ncbi.nlm.nih.gov/pubmed/23109809
http://dx.doi.org/10.2147/OTT.S36683