Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-β type II receptor (sTGFβRII) gene transfer

PURPOSE: To explore (i) the potential of polyethylenimine (PEI)-DNA nanoparticles as a vector for delivering genes into human corneal fibroblasts, and (ii) whether the nanoparticle-mediated soluble extracellular domain of the transforming growth factor–β type II receptor (sTGFβRII) gene therapy coul...

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Detalles Bibliográficos
Autores principales: Sharma, Ajay, Rodier, Jason T., Tandon, Ashish, Klibanov, Alexander M., Mohan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482172/
https://www.ncbi.nlm.nih.gov/pubmed/23112572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482172/
https://www.ncbi.nlm.nih.gov/pubmed/23112572

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