A Cancer Vaccine Induces Expansion of NY-ESO-1-Specific Regulatory T Cells in Patients with Advanced Melanoma

Cancer vaccines are designed to expand tumor antigen-specific T cells with effector function. However, they may also inadvertently expand regulatory T cells (Treg), which could seriously hamper clinical efficacy. To address this possibility, we developed a novel assay to detect antigen-specific Treg...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebert, Lisa M., MacRaild, Sarah E., Zanker, Damien, Davis, Ian D., Cebon, Jonathan, Chen, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482213/
https://www.ncbi.nlm.nih.gov/pubmed/23110239
http://dx.doi.org/10.1371/journal.pone.0048424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482213/
https://www.ncbi.nlm.nih.gov/pubmed/23110239
http://dx.doi.org/10.1371/journal.pone.0048424

Ejemplares similares