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A Cancer Vaccine Induces Expansion of NY-ESO-1-Specific Regulatory T Cells in Patients with Advanced Melanoma

Cancer vaccines are designed to expand tumor antigen-specific T cells with effector function. However, they may also inadvertently expand regulatory T cells (Treg), which could seriously hamper clinical efficacy. To address this possibility, we developed a novel assay to detect antigen-specific Treg...

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Detalles Bibliográficos
Autores principales:	Ebert, Lisa M., MacRaild, Sarah E., Zanker, Damien, Davis, Ian D., Cebon, Jonathan, Chen, Weisan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482213/ https://www.ncbi.nlm.nih.gov/pubmed/23110239 http://dx.doi.org/10.1371/journal.pone.0048424

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