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The Impact of cHS4 Insulators on DNA Transposon Vector Mobilization and Silencing in Retinal Pigment Epithelium Cells

DNA transposons have become important vectors for efficient non-viral integration of transgenes into genomic DNA. The Sleeping Beauty (SB), piggyBac (PB), and Tol2 transposable elements have distinct biological properties and currently represent the most promising transposon systems for animal trans...

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Detalles Bibliográficos
Autores principales: Sharma, Nynne, Hollensen, Anne Kruse, Bak, Rasmus O., Staunstrup, Nicklas Heine, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482222/
https://www.ncbi.nlm.nih.gov/pubmed/23110238
http://dx.doi.org/10.1371/journal.pone.0048421